The International Institute of Genetics of Diabetes (INIGEDIA) wants to help endocrinologist and paediatric endocrinologist professionals in the research, diagnosis and treatment of patients susceptible to have any kind of Monogenic Diabetes.
We offer consultation service for the genetic testing and treatment recommendation depending on the clinical phenotype and genetic results. In really interesting cases or families with numerous members affected we have research funding enable the genetic testing needed without cost for the family or the referral doctor.
The test are made using the most advanced technology in Denmark in the Section of Metabolic Genetics Laboratory, Faculty of Health and Medical Sciences of the University of Copenhagen (METAGENE)
The blood sample will ONLY be tested for changes in known Monogenic Diabetes genes (GCK, HNF1A, HNF4A, HNF1B, NEUROD1, INS, CEL, PDX1, PAX4, BLK, KLF11, KCNJ11 and ABCC8). Once the gene mutation has been described, the patient can choose either to discard de DNA or allow INIGEDIA to store it at -20ºC at the Section of Metabolic Genetics Laboratory, Faculty of Health and Medical Sciences of the University of Copenhagen (METAGENE) in order to study genotype-phenotype correlations (i.e. modification of the diabetic phenotype due to
other mutations discarded). However, in the case the first genetic study does not show any mutation in the known Monogenic Diabetes genes, the DNA will be stored at -20ºC at the University of Copenhagen and may be retested as new Monogenic Diabetes genes are discovered.
You can consult a case filling the clinical history in the case form or get in contact with us through firstname.lastname@example.org